Comparison of ionic polymers in the targeted drug delivery applications as the coating materials on the Fe3O4 nanoparticles

Bekaroglu, Maide; Alemdar, Ayse; Isci, Sevim

doi:10.1016/j.msec.2019.109838

Comparison of ionic polymers in the targeted drug delivery applications as the coating materials on the Fe3O4 nanoparticles

Atıf İçin Kopyala

Bekaroglu M. G., Alemdar A., Isci S.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, cilt.103, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 103
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.msec.2019.109838
Dergi Adı: MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
İstanbul Teknik Üniversitesi Adresli: Evet

Özet

The objective of the study was to obtain multifunctional core shell nanostructures of superparamagnetic iron oxide nanoparticles (Fe3O4) coated with various ionic biopolymers that can optimize toxicity to healthy cells, colloidal instabilities and drug loading capacities. These nanostructures can also allow drug delivery to tumor tissue because of their magnetic properties, accumulation and drug release at tumor site could be controlled by means of an external magnetic field.