Comparison of ionic polymers in the targeted drug delivery applications as the coating materials on the Fe3O4 nanoparticles


Bekaroglu M. G. , Alemdar A., Isci S.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, cilt.103, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 103
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.msec.2019.109838
  • Dergi Adı: MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS

Özet

The objective of the study was to obtain multifunctional core shell nanostructures of superparamagnetic iron oxide nanoparticles (Fe3O4) coated with various ionic biopolymers that can optimize toxicity to healthy cells, colloidal instabilities and drug loading capacities. These nanostructures can also allow drug delivery to tumor tissue because of their magnetic properties, accumulation and drug release at tumor site could be controlled by means of an external magnetic field.