Comparison of ionic polymers in the targeted drug delivery applications as the coating materials on the Fe3O4 nanoparticles


Bekaroglu M. G. , Alemdar A., Isci S.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, vol.103, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 103
  • Publication Date: 2019
  • Doi Number: 10.1016/j.msec.2019.109838
  • Title of Journal : MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS

Abstract

The objective of the study was to obtain multifunctional core shell nanostructures of superparamagnetic iron oxide nanoparticles (Fe3O4) coated with various ionic biopolymers that can optimize toxicity to healthy cells, colloidal instabilities and drug loading capacities. These nanostructures can also allow drug delivery to tumor tissue because of their magnetic properties, accumulation and drug release at tumor site could be controlled by means of an external magnetic field.