Santalum Genus: phytochemical constituents, biological activities and health promoting-effects

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Sharifi-Rad J., Quispe C., Turgumbayeva A., Mertdinç Z., Tutuncu S., Aydar E. F., ...Daha Fazla

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES, cilt.78, ss.9-25, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 78
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1515/znc-2022-0076
  • Dergi Adı: ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.9-25
  • Anahtar Kelimeler: bioactivities, clinical studies, essential oil, phytochemistry, safety, sandalwood, INDIAN SANDALWOOD, ALBUM L., ESSENTIAL OILS, TRADITIONAL MEDICINE, TAXONOMIC REVISION, CONTACT-DERMATITIS, ALPHA-SANTALOL, CARBON-DIOXIDE, BETA-SANTALOL, IN-VITRO
  • İstanbul Teknik Üniversitesi Adresli: Evet

Özet

Santalum genus belongs to the family of Santalaceae, widespread in India, Australia, Hawaii, Sri Lanka, and Indonesia, and valued as traditional medicine, rituals and modern bioactivities. Sandalwood is reported to possess a plethora of bioactive compounds such as essential oil and its components (alpha-santalol and beta-santalol), phenolic compounds and fatty acids. These bioactives play important role in contributing towards biological activities and health-promoting effects in humans. Pre-clinical and clinical studies have shown the role of sandalwood extract as antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroleptic, antihyperglycemic, antihyperlipidemic, and anticancer activities. Safety studies on sandalwood essential oil (EO) and its extracts have proven them as a safe ingredient to be utilized in health promotion. Phytoconstituents, bioactivities and traditional uses established sandalwood as one of the innovative materials for application in the pharma, food, and biomedical industry.