Computation of variance in compartment model parameter estimates from dynamic PET data

Kamasak M. E.

MEDICAL PHYSICS, cilt.39, sa.5, ss.2638-2648, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 5
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1118/1.3702456
  • Dergi Adı: MEDICAL PHYSICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2638-2648
  • İstanbul Teknik Üniversitesi Adresli: Evet

Özet

Purpose: This paper investigates the validity of the analytical framework for variance ("analytical variance") in kinetic parameter and macroparameter estimations. Analytical variance is compared against the variance obtained from Monte Carlo simulations ("MC variance") for two different compartment models at different noise levels.