The synthesis of new silicon phthalocyanines and analysis of their photochemical and biological properties

Demirkapi D., SIRIN A., TURANLI-YILDIZ B., Çakar Z. P., Sesalan B. Ş.

SYNTHETIC METALS, vol.187, pp.152-159, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 187
  • Publication Date: 2014
  • Doi Number: 10.1016/j.synthmet.2013.11.001
  • Journal Name: SYNTHETIC METALS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.152-159
  • Keywords: Silicon phthalocyanine, Quaternization, Zwitterionic, Singlet oxygen, Photoinactivation, Saccharomyces cerevisiae, QUANTUM YIELDS, PHOTODYNAMIC TREATMENT, OXYGEN, CELLS, YEAST, PHOTOSENSITIZERS, PHOTOPHYSICS, AGGREGATION, STATE
  • Istanbul Technical University Affiliated: Yes

Abstract

In this study, new silicon phthalocyanine compounds were synthesized. The new neutral compound 3 is reacted with excess dimethyl sulfate to obtain quaternized derivative; 3Q. For the synthesis of the zwitterionic complex, 3 and excess 1,3-propanedisultone were reacted in dry dimethylformamide for 24h under nitrogen atmosphere. The structures of all compounds were characterized by using spectrophotometric techniques. Experiments which include the singlet oxygen generation and photoinactivation of the yeast Saccharomyces cerevisiae both in the absence and presence of light indicated that these compounds can be potentially used in photodynamic therapy or photoinactivation of some microorganisms. (C) 2013 Elsevier B.V. All rights reserved.