A study on the percolation characteristics of single-phase flow in rough fractures at high rates representing hydraulic fracturing conditions is presented. Two-dimensional transparent models of fractures obtained from different rock types (granite, marble and limestone) were reproduced by molding. To represent typical hydraulic fracturing fluids, water and polymeric solutions were injected at a constant flow rate. The inlet pressure was continuously monitored to correlate the permeability changes due to surface roughness of fractures. The fluid distributions were also mapped using the images acquired through the experiments. The surface roughness was quantified using three fractal methods (variogram, power spectral density, and triangular prism) and the ratio of total and planar areas, and these parameters were correlated to the percent wetted areas and pressure drop (i.e., permeability). This exercise was performed on joint type and horizontally displaced (sheared) model fractures.