Spray-Dried Mesoporous Hydroxyapatite Chitosan Biocomposites


POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING, vol.54, no.11, pp.1172-1183, 2015 (SCI-Expanded) identifier identifier


In this study, hydroxyapatite-chitosan composites with weight ratio of 1:0.1 were produced by spray-drying technique using two different inlet temperature. Besides, the effect of weight change of hydroxyapatite on composites was investigated on composites which were spray-dried in the selected temperature. Synthesized hydroxyapatite-chitosan samples were characterized using Fourier transform infrared microscopy, scanning electron microscopy, X-ray fluorescence spectroscopy, Brunauer-Emmet-Teller method, and X-ray diffraction. Particle size measurements were also performed in this content. Simulated body fluid studies were conducted on selected samples. According to results, hydroxyapatite-chitosan sample was successfully synthesized. Spray-dried mesoporous microspheres with high surface areas could be suitable for biomedical usage.