Effect of propylthiouracil on adenosine deaminase activity and thyroid function in patients with psoriasis


Kose K., Utas S., Yazici C., Akdas A., Kelestimur F.

BRITISH JOURNAL OF DERMATOLOGY, vol.144, no.6, pp.1121-1126, 2001 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 144 Issue: 6
  • Publication Date: 2001
  • Doi Number: 10.1046/j.1365-2133.2001.04221.x
  • Title of Journal : BRITISH JOURNAL OF DERMATOLOGY
  • Page Numbers: pp.1121-1126

Abstract

Background T-cell activation has been implicated in the pathogenesis of psoriasis; adenosine deaminase (ADA) activity has been considered as a marker of T-cell activation. The antithyroid drug propylthiouracil (PTU) has recently been shown to have beneficial effects on psoriatic lesions, probably by acting on the immune system.